"Muthi" is the term for traditional medicine in Southern Africa. After the European colonization Muthi and African healers were perceived as unscientific and ineffective. But urbanization and the rise of consumer culture radically changed traditional practices and created a growing market for traditional herbal medicine which threatens sustainability and biodiversity. The pharmaceutical industry has also joined in the trend, ignoring the cultural and spiritual contexts of the plants. The film follows the chains of value which include plant collectors, petty traders and traditional healers and touches on issues around tradition and modernity, indigenous knowledge and alternative medicine in post-colonial contexts.